Mackenzie Lab

In our research group, we use mouse transgenics and optogenetics to unravel brain mechanisms of importance to motions and emotions, and that are dysfunctional in disorders such as Parkinson’s disease and addictions.  We target brain circuits involving the ventral tegmental area (VTA) and the subthalamic nucleus (STN) to identify and analyse reward/aversion-driven processes and how these guide decision-making and motivated behaviour, as well as processes of initating and performing intended, volitional movements. 

Learn more about our ongoing research.

Our funders


Hållsten Research Foundation