Danio Readout service facility

Leading technologies for genetic disease modelling and substance exposure integrated with phenotypic evaluation in the zebrafish embryo.

Our vision

Zebrafish animal model has been rapidly developing and is now recognized as a complementary system to rodents for studying bases of human diseases. The possibility of performing automated high-throughput screens at low-cost is unique for this model organism. DanioReadout offers a versatile pipeline with a palette of advanced tools for embryo manipulation and phenotype characterisation.

Read more at the DanioReadout main website.

What we do

DanioReadout technology

Genetic models development based on the CRISPR/Cas9 technology

  • Modeling a human genetic disorder
  • Gene and gene regulatory elements function investigation
  • Candidate genes verification

Zebrafish embryo compound exposure

  • Toxicological screens
  • Preclinical drug validation
  • Automated cardiac readout and phenotype assessment

Cancer modelling service

  • Cancer growth and metastasis quantification
  • Cell culture based and patient-derived samples xenotransplantation
  • Service can be combined with potential therapeutics testing

User experiences

“I have worked closely with the zebrafish facility in Uppsala and GEZ since 2012 and have gotten excellent support in a various projects, including the construction of novel zebrafish lines.”

- PI, University of Gothenburg, Inst. for Neuroscience and Physiology

Excellent in generating new genetic models, developing their offer to the user needs and expanding their expertise to unsure the users can perform world-standard research.

- PI, Uppsala University, IGP

“The service provided by the facility is essential to our work. The expertise the facility provides is unique in Sweden and has had a wider positive impact allowing many labs to have access to advanced techniques that no single lab can build alone”

- PI, Karolinska Institute, Department of Neuroscience

Last modified: 2022-10-19