Our research areas
The Molecular Toxicology and Epigenetics (EpiTox) group focusses on understanding molecular mechanisms underlying the effects of endocrine disrupting chemicals on (neuro)development. In particular, we are focussing on epigenetic changes, i.e. long-lasting changes in gene regulation that do not involve alteration in the DNA sequence.
Contact person: Prof. Joëlle Rüegg
The avian embryo develops in the egg separate from the mother. This gives opportunities to study effects from chemicals directly on the embryo without maternal influence. We inject various environmental pollutants into the yolk or air sac of the eggs and then we carry out different kinds of analyses at different stages of embryo development. We mainly use chicken and quail eggs in these studies.
Contact: Björn Brunström
Using the frog as a model we investigate endocrine disruption, developmental and reproductive toxicity using methods that range over several levels of biological organisation including molecular, physiological, and behavioural. We explore effects of environmental chemicals on the sex hormone system, metabolic and neuroendocrine systems.
Contact person: Assoc. Prof. Cecilia Berg
The zebrafish is a small vertebrate whose development can be directly monitored by microscope. In our studies, we use zebrafish as a model to investigate the effects of environmental pollutants on the body's metabolism and fat tissue development. Among other things, we have seen that zebrafish fry develop more fat cells and get altered metabolism if exposed to mixtures of anthropogenic chemicals, which are found in human blood.
Contact person: Dr. Maria Jönsson
We create and explore multiparametric environments to expand our understanding of the effects of physico-chemical perturbations on organisms in their natural habitat.
Contact person: Dr. Lars Behrendt
Developmental neurotoxicity in neonatal mammals
Contact: Sonja Buratovic