Our research areas
The Molecular Toxicology and Epigenetics (EpiTox) group focusses on understanding molecular mechanisms underlying the effects of endocrine disrupting chemicals on (neuro)development. In particular, we are focussing on epigenetic changes, i.e. long-lasting changes in gene regulation that do not involve alteration in the DNA sequence.
Contact: Prof. Joëlle Rüegg
Using the frog as a model we investigate endocrine disruption, developmental and reproductive toxicity using methods that range over several levels of biological organisation including molecular, physiological, and behavioural. We explore effects of environmental chemicals on the sex hormone system, metabolic and neuroendocrine systems.
Contact: Assoc. Prof. Cecilia Berg
The zebrafish is a small vertebrate whose development can be directly monitored by microscope. In our studies, we use zebrafish as a model to investigate the effects of environmental pollutants on the body's metabolism and fat tissue development. Among other things, we have seen that zebrafish fry develop more fat cells and get altered metabolism if exposed to mixtures of anthropogenic chemicals, which are found in human blood.
Contact: Dr. Maria Jönsson
We create and explore multiparametric environments to expand our understanding of the effects of physico-chemical perturbations on organisms in their natural habitat.
Contact: Dr. Lars Behrendt
Contact: Monika Schmitz
We live in a constantly changing environment! Changes in environmental factors, such as temperature, oxygen levels or humidity, can influence physiological processes and molecular pathways in all living animals. Among others, environmental changes can affect the epigenome of the organisms, which may alter the expression of their genes and consequently produce long-term changes in their phenotypes.
Kontaktperson: Dr. Carlos Guerrero Bosagna
Former research groups:
The avian embryo develops in the egg separate from the mother. This gives opportunities to study effects from chemicals directly on the embryo without maternal influence. We inject various environmental pollutants into the yolk or air sac of the eggs and then we carry out different kinds of analyses at different stages of embryo development. We mainly use chicken and quail eggs in these studies.
Contact: Björn Brunström
Developmental neurotoxicity in neonatal mammals
Contact: Sonja Buratovic